EPSRC funded post-graduate students and post-doctoral researchers with an interest in chemistry and allied small-molecule mass spectrometry.
If you're a university Mass Spectrometry Operator and are interested in training please contact us to discuss, as we can offer courses tailored to your specific needs.
The 30th Anniversary Symposium and Summer School 2017 is due to be held on 10–13 July at Swansea University Medical School.
FREE!! accommodation, lunch and breakfast for all delegates.
A "must do" for every postgraduate.
Helpful in making decisions about best techniques for our compounds, tutorials were great.
A course that gives you everything you need to tackle your mass spec problems.
All lectures were very clear and well presented, good balance between lectures and tutorials.
The Summer School was fabulous, well organized with magnificently flowing lectures. Each of the lectures was broadcast with intuitive expertise and mirrored with useful images.
Very informative, excellent resources and knowledgeable speakers.
Learnt a lot for different techniques, good theoretical information and practical sessions.
Great course, excellent speakers (knowledgeable and very friendly), a lot of material covered in good time and good amount of practical examples. Very detailed and extremely useful.
Well planned, well organised with lots of available resources.
Very good - talks and tutorials help clarifying all the concepts. Excellent course.
It was wonderful experience, go so much knowledge, great presentations/tutorial sessions.
Friendly staff, answered lots of my questions which helps with my job at Cardiff. Good knowledge about everything.
I now feel I can interpret mass spectra much more confidently. I also have a better understanding of each technique and when each should be applied. Overall, a very rewarding experience.
The summer school managed to fit in a useful mix of theory and practical tutorial work led by a range of skilled and knowledgeable presenters – very helpful!
NMSF Summer School shows the exact way of analysing the mass spectrum. It’s really improved the knowledge about mass spec.
Good training regarding mass spec interpretation and analysis of spectra. Different types of ionisation methods well covered as well.
Got to know many things that need to be considered both theoretical and practical aspects.
Really good presentations.
Good combinations of presentations and problems.
Excellent notes − act as a good refresher for undergraduate learning and also further understanding. Very good presentations − good visual aids in PowerPoints.
Good focus on the mass spec theory. Quite intense but we have the material available to review as necessary. Practical session on pump/sources very useful. LC workshop excellent. Good range of information covered. Lots to think about.
It was very informative and helpful with very friendly staff and people who were willing to help with anything.
It was a great experience meeting the NMSF team and learning so much from them. It was all good in general.
It showed me ways in which I can improve the precision and sensitivity of my method and easy things that can be really helpful for good practise. It was a little bit of all the fields, which was useful for me.
Very useful. Helped understand a number of queries I had.
The order of presentations and tutorials kept everyone focussed. I would recommend to everyone.
Learned several new things about analysing data (my top priority). Also, every staff member was very helpful, friendly and knowledgeable.
I found the school very informative at facilitating my understanding of spectrometry. It was good to be taught by experts.
I have learned lots over the past few days. The Summer School was excellent!
Good quality of material provided, tutorials were useful. Very nice staff and well organised.
Interesting that spectra can be used to calculate so many things.
Very comprehensive, excellent presentations, staff very helpful. Course booklet will be useful reference guide for future. Always nice to meet and compare notes with other researchers. Excellent coverage from basics to more specialised areas.
Mass spectrometry involves the ionization of a sample to produce either positive or negative ions. These are accelerated in a vacuum system and the mass of the intact molecule determined. In addition the masses of fragments produced during the ionisation processes can be determined to give structural information. Accurate mass measurement of the molecular ions can lead to the determination of elemental composition. A study of the fragmentation patterns can lead to the identification of unknown reaction products through computer library matching. “Soft” ionization techniques such as Chemical Ionization, (CI), Liquid Secondary Ion Mass Spectrometry (LSIMS, - often called FAB), Matrix-assisted Laser Desorption / Ionization (MALDI), Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) can be used to reduce fragmentation and enhance the abundance of the intact molecular ion.
Coupling of chromatography (gas or liquid) to mass spectrometry allows separation and analysis of mixtures. These techniques of GC/MS and LC/MS assist in the identification of organic compounds from a wide variety of sources: synthetic, natural or biomedical.
Swansea University offers a range of activities to School and College students via their Outreach Programme. Including the following two interactive talks given by the Mass Spectrometry Facility staff:
Investigation into Accurate Mass Capability of MALDI-TOFMS, with respect to Organometallic and Highly Conjugated Compounds - Talk given by Mark Wyatt at the 27th BMSS Conference (2004) in Derby, UK.
Mass Spectral Quality - Talk given by Bridget Stein at RSC meeting in London on 6th June 2006.
MALDI-TOFMS analysis of coordination and organometallic complexes: a nic(h)e area to work in - Talk given by Mark Wyatt at the 32nd BMSS Conference (2011) in Cardiff, UK.
ChemistryViews, Mark F. Wyatt You're Studying What by MALDI-TOFMS!?
Summary of J. Mass Spectrom., 2011, 46, 712-719. DOI: 10.1002/jms.1957.
Xiaojuan Bai, Bridget K. Stein, Keith Smith, David H. Isaac Effects of reprocessing on additives in ABS plastics, detected by gas chromatography/mass spectrometry Prog. Rubber Plast. Re., 2012, 28, 1-14.
Vicki Barwick, John Langley, Tony Mallet, Bridget Stein, Ken Webb
Best practice guide for generating mass spectra
produced with support from the Valid Analytical Measurement (VAM) programme (www.vam.org.uk)
Date: 29/01/2007 Ref No: ISBN: 978 0 948926 24 2 Type: Guide
Ken Webb, Tony Bristow, Mike Sargent and Bridget Stein,
Methodology for Accurate Mass Measurement of Small Molecules - Best Practice Guide
produced with support from the VIMMS programme (www.vam.org.uk)
Date: November 2004 Ref No: ISBN 0-948926-22-8 Type: Guide
Anthony W. T. Bristow and Kenneth S. Webb
Intercomparison study on accurate mass measurement of small molecules in mass spectrometry.
J. Am. Soc. Mass Spectrom., Vol, 14, Issue 10, October 2003, Pages 1086-1098